12-07-2016, 12:18 AM
Short-Term Effects of Cannabis Therapy on Spasticity in MSINVESTIGATOR: Jody Corey-Bloom, M.D., Ph.D.
STUDY LOCATION: University of California, San Diego
PROJECT TITLE: Short-Term Effects of Cannabis Therapy on Spasticity in MS
PROJECT TYPE: Clinical Study
STATUS: COMPLETE
RESULTS:
Thirty-seven participants were randomized at the start of the study, 30 of whom completed the trial. Treatment with smoked cannabis resulted in a significant reduction in spasticity using an objective clinician-rated measure. The placebo-controlled trial also resulted in reduced perception of pain, although participants also reported short-term, adverse cognitive effects and increased fatigue. No serious adverse events occurred during the trial.
The full results of this study have been published in <a data-ipb="nomediaparse" href="http://www.ncbi.nlm.nih.gov/pubmed/22586334">CMAJ</a>.
ABSTRACT:
Multiple Sclerosis (MS) is the most common debilitating neurologic disease of young people, affecting at least 250,000 persons in the US, often between the ages of 20 and 40. Symptom manifestation varies considerably from person to person; however, one frequently noted concomitant is spasticity, which causes pain, spasms, loss of function and difficulties in nursing care. The present application is designed to explore the short-term effectiveness and safety of medicinal cannabis on spasticity in patients with MS. There has been significant public,....
<a data-ipb="nomediaparse" href="http://www.cmcr.ucsd.edu/index.php/2015-11-20-20-52-15/completed-studies/34-short-term-effects-of-cannabis-therapy-on-spasticity-in-ms">http://www.cmcr.ucsd.edu/index.php/2015-11-20-20-52-15/completed-studies/34-short-term-effects-of-cannabis-therapy-on-spasticity-in-ms</a>
STUDY LOCATION: University of California, San Diego
PROJECT TITLE: Short-Term Effects of Cannabis Therapy on Spasticity in MS
PROJECT TYPE: Clinical Study
STATUS: COMPLETE
RESULTS:
Thirty-seven participants were randomized at the start of the study, 30 of whom completed the trial. Treatment with smoked cannabis resulted in a significant reduction in spasticity using an objective clinician-rated measure. The placebo-controlled trial also resulted in reduced perception of pain, although participants also reported short-term, adverse cognitive effects and increased fatigue. No serious adverse events occurred during the trial.
The full results of this study have been published in <a data-ipb="nomediaparse" href="http://www.ncbi.nlm.nih.gov/pubmed/22586334">CMAJ</a>.
ABSTRACT:
Multiple Sclerosis (MS) is the most common debilitating neurologic disease of young people, affecting at least 250,000 persons in the US, often between the ages of 20 and 40. Symptom manifestation varies considerably from person to person; however, one frequently noted concomitant is spasticity, which causes pain, spasms, loss of function and difficulties in nursing care. The present application is designed to explore the short-term effectiveness and safety of medicinal cannabis on spasticity in patients with MS. There has been significant public,....
<a data-ipb="nomediaparse" href="http://www.cmcr.ucsd.edu/index.php/2015-11-20-20-52-15/completed-studies/34-short-term-effects-of-cannabis-therapy-on-spasticity-in-ms">http://www.cmcr.ucsd.edu/index.php/2015-11-20-20-52-15/completed-studies/34-short-term-effects-of-cannabis-therapy-on-spasticity-in-ms</a>