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08-07-2017, 10:12 AM (This post was last modified: 08-07-2017, 10:13 AM by Purple Power.)
Know Your Medicine: CBN
<a data-ipb="nomediaparse" href="https://www.marijuana.com/news/2017/08/know-your-medicine-cbn/#respond">0</a> By <span><a data-ipb="nomediaparse" href="https://www.marijuana.com/news/author/bgoldstein/" title="Posts by Bonni Goldstein, M.D.">Bonni Goldstein, M.D.</a> </span> on <span> </span>
<span>August 7th, 2017</span>
There are over 100 phytocannabinoids in the cannabis plant with the two major cannabinoids THC (delta-9-tetrahydrocannabinol) and CBD (cannabidiol) as the most prominent and researched. Dr. Raphael Mechoulam, the renowned researcher who discovered the chemical structure of THC in 1964, was the first to hypothesize that phytocannabinoids work via the entourage effect. This means that the compounds in the plant work together synergistically to enhance the therapeutic benefits and minimize unwanted side effects. Although many understand the medicinal properties of the two major cannabinoids, lets take a look at cannabinol (CBN), another anti-inflammatory, anticonvulsant and antibacterial medicinal cannabinoid.
Cannabinol was the first phytocannabinoid ever isolated (1896 by Wood <i>et. al</i>.) with its chemical structure partially elucidated by R.S. Cahn in 1932 and fully determined by two research groups in 1940 (Todd <i>et al.</i>, and Adams <i>et. al.</i>). CBN was thought to be responsible for the intoxicating effects of cannabis until 1964 when Israeli researchers Drs. Gaoni and Mechoulam isolated THC and found it to be the responsible for the well-known psychoactive effects of the plant. Further research found CBN to be a breakdown product of THC oxidation, which happens as the harvested flower ages. Only traces of CBN are found in fresh flowers, with higher levels indicating aged flower......
<a data-ipb="nomediaparse" href="https://www.marijuana.com/news/2017/08/know-your-medicine-cbn/">https://www.marijuana.com/news/2017/08/know-your-medicine-cbn/</a>
<a data-ipb="nomediaparse" href="https://www.marijuana.com/news/2017/08/know-your-medicine-cbn/#respond">0</a> By <span><a data-ipb="nomediaparse" href="https://www.marijuana.com/news/author/bgoldstein/" title="Posts by Bonni Goldstein, M.D.">Bonni Goldstein, M.D.</a> </span> on <span> </span>
<span>August 7th, 2017</span>
There are over 100 phytocannabinoids in the cannabis plant with the two major cannabinoids THC (delta-9-tetrahydrocannabinol) and CBD (cannabidiol) as the most prominent and researched. Dr. Raphael Mechoulam, the renowned researcher who discovered the chemical structure of THC in 1964, was the first to hypothesize that phytocannabinoids work via the entourage effect. This means that the compounds in the plant work together synergistically to enhance the therapeutic benefits and minimize unwanted side effects. Although many understand the medicinal properties of the two major cannabinoids, lets take a look at cannabinol (CBN), another anti-inflammatory, anticonvulsant and antibacterial medicinal cannabinoid.
Cannabinol was the first phytocannabinoid ever isolated (1896 by Wood <i>et. al</i>.) with its chemical structure partially elucidated by R.S. Cahn in 1932 and fully determined by two research groups in 1940 (Todd <i>et al.</i>, and Adams <i>et. al.</i>). CBN was thought to be responsible for the intoxicating effects of cannabis until 1964 when Israeli researchers Drs. Gaoni and Mechoulam isolated THC and found it to be the responsible for the well-known psychoactive effects of the plant. Further research found CBN to be a breakdown product of THC oxidation, which happens as the harvested flower ages. Only traces of CBN are found in fresh flowers, with higher levels indicating aged flower......
<a data-ipb="nomediaparse" href="https://www.marijuana.com/news/2017/08/know-your-medicine-cbn/">https://www.marijuana.com/news/2017/08/know-your-medicine-cbn/</a>