Scientists Discover How Cannabis Slows Alzheimer’s Disease

[KarrMcDebt]

http://www.truthonpot.com/2013/07/09/stu...w-disease/

[eloquentsolution]

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<div>great link, karr! for ease of access:


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Home > Living Well > Aging Well > Scientists Discover How Cannabis Slows Alzheimers Disease
</div> Scientists Discover How Cannabis Slows Alzheimers Disease<div>By TruthOnPot.com on July 9, 2013</div>

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<p class=""><i>Clumps of protein known as beta-amyloid plaque are a key trait of Alzheimers and contribute to the progression and symptoms of the disease. New evidence points to a unique role of marijuana in removing this plaque from the brain.</i>


TruthOnPot.com Previous studies suggest a role of cannabis in slowing the progression of Alzheimers and now scientists can explain why.

Researchers at the Roskamp Institute in Florida have shown for the first time how cannabinoids the active chemicals in marijuana are able to reduce the build-up of a key indicator of Alzheimers disease.

For long, scientists have linked the loss of cell and brain tissue in Alzheimers to abnormal structures called beta-amyloid (A) plaque. Levels of plaque in a patients brain can even predict the severity of symptoms and tissue damage suffered.

Published last week in the Molecular and Cellular Neuroscience journal, the new findings reveal how cannabinoids reverse the build-up of plaque in Alzheimers by expelling it from the brain.

(MORE: Can Marijuana Help Combat Brain Aging?)

The team, led by Corbin Bachmeier, Ph.D, explains that Alzheimers is not a result of abnormal production of the plaque, but the result of impaired A clearance from the brain.

Their results suggest that chemicals in marijuana can aid the plaque in crossing the blood-brain barrier, a process that allows plaque levels to be kept low in healthy people. Previous studies show that this process is blocked in patients with Alzheimers disease.

While this study was the first to identify this unique function of cannabinoids, it confirms the results of prior research linking the chemicals to a reduction in both plaque levels and Alzheimers symptoms.


<p class=""><i>Dr. Tim Karl, like most neuro-scientists, works mostly with rodent models</i>

Whats more, others suggest cannabinoids have a variety of effects that could be helpful in treating the disorder.Earlier this year, Tim Karl, Ph.D, a senior investigator at Neuroscience Research Australia who was not involved with the current study, found that mice with Alzheimers experienced dramatic improvements in memory after treatment with cannabidiol (CBD).

CBD is one of over 60 cannabinoids found in marijuana and has captured the attention of researchers due to its lack of psychoactive effects.

It basically brings the performance of the animals back to the level of healthy animals, Karl told Sydney Morning Herald.



You could say it cured them, but we will have to go back and look at their brains to be sure.


Earlier studies point to the anti-inflammatory properties of cannabinoids as useful in Alzheimers.

Gary Wenk, Ph.D, a professor of neuroscience, immunology and medical genetics at Ohio State University, was one of the first scientists to suggest this.

Ive been trying to find a drug that will reduce brain inflammation and restore cognitive function in rats for over 25 years; cannabinoids are the first and only class of drugs that have ever been effective, he told Time Magazine.

He believes that stigma still hinders marijuana-based medicine from being widely accepted, but is hopeful that things will change.



I think that the perception about this drug is changing and in the future people will be less fearful.


Alzheimers disease continues to be a leading cause of disability among the growing population of seniors. Without a breakthrough in treatment, the number of Alzheimers cases are expected to triple over the next 50 years.

(MORE: Medical Marijuana and Parkinsons Disease)

The study was published online on July 3, 2013 and funded by the Roskamp Institute, a not-for-profit research foundation.

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[Transcendence]

Great news! Florida of all places.... [img]/emoticons/yahooimages_egyptian.gif[/img]

[KarrMcDebt]

Nice, Thanks ES. [img]<fileStore.core_Emoticons>/smile.png[/img]/emoticons/smile@2x.png 2x" width="20" height="20">

[Vapeit]

2 thumbs up on the link Karr, thanks!

[Graywolf]

Good post! Thanks!

[EDDIEKIRK]

Thanks KarrMcDebt I love this

[xbrpete]

Very informative post karr!

[alz+]

thank you