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04-16-2012, 10:46 PM
Tourette's Syndrome
The American Medical Association stated in an online report "Medical Marijuana (A-01)" (accessed on Jan. 10, 2007): "Only limited data exist on the effects of marijuana in patients with Tourettes syndrome who respond inadequately to standard treatment, consisting of 4 case histories that report beneficial effects of smoked marijuana and 1 who reported substantial benefit from oral 9-THC (10 mg)."
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![[Image: 23consults_tourettes-blogSpan.jpg]](http://graphics8.nytimes.com/images/2010/02/23/health/23consults_tourettes/23consults_tourettes-blogSpan.jpg)
Louis Centanni smokes marijuana daily for relief from the tics of Tourettes syndrome. Theres one thing that helps my Tourettes more than anything, and its marijuana, says Louis Centanni, the 24-year-old actor and comedian featured in Patient Voices: Tourettes Syndrome. Dr. Robert A. King and Dr. James F. Leckman of the Yale School of Medicine, who recently joined the Consults blog to answer readers questions about Tourettes, here respond to readers asking about the use of marijuana for easing the tics, vocalizations and jerking movements of the syndrome.
Is Marijuana Effective for Tourettes?
Q. Clinical studies have shown that marijuana can be effective in relieving the symptoms of this disease: http://norml.orgPaul Kuhn, Nashville
Q. I see that the first patient with Tourettes featured in the Patient Voices series uses marijuana to calm his tics. How do the chemicals in marijuana help Tourettes patients, and do other depressant-type drugs also help? Rafi, N.Y.
A. Dr. King and Dr. Leckman respond:
A number of individuals with severe Tourettes regularly use marijuana and report that it calms them and eases their tics. And a few randomized clinical trials of delta 9-tetrahydrocannabinol, or THC, the active ingredient in marijuana, have been carried out. Some of the investigators are convinced that THC and related compounds in marijuana called cannabinoids are helpful; others are more equivocal.
The most comprehensive review to date of the efficacy of cannabinoids in Tourettes comes from a research group in Britain, the Cochrane Collaboration, that reviewed all the available data. They found that the improvements in tic frequency and severity were small and were only detected by some of the outcome measures. The group concluded that there is not enough evidence to support the use of cannabinoids in treating tics and obsessive-compulsive behavior in people with Tourettes syndrome.
More
The American Medical Association stated in an online report "Medical Marijuana (A-01)" (accessed on Jan. 10, 2007): "Only limited data exist on the effects of marijuana in patients with Tourettes syndrome who respond inadequately to standard treatment, consisting of 4 case histories that report beneficial effects of smoked marijuana and 1 who reported substantial benefit from oral 9-THC (10 mg)."
More
Louis Centanni smokes marijuana daily for relief from the tics of Tourettes syndrome. Theres one thing that helps my Tourettes more than anything, and its marijuana, says Louis Centanni, the 24-year-old actor and comedian featured in Patient Voices: Tourettes Syndrome. Dr. Robert A. King and Dr. James F. Leckman of the Yale School of Medicine, who recently joined the Consults blog to answer readers questions about Tourettes, here respond to readers asking about the use of marijuana for easing the tics, vocalizations and jerking movements of the syndrome.
Is Marijuana Effective for Tourettes?
Q. Clinical studies have shown that marijuana can be effective in relieving the symptoms of this disease: http://norml.orgPaul Kuhn, Nashville
Q. I see that the first patient with Tourettes featured in the Patient Voices series uses marijuana to calm his tics. How do the chemicals in marijuana help Tourettes patients, and do other depressant-type drugs also help? Rafi, N.Y.
A. Dr. King and Dr. Leckman respond:
A number of individuals with severe Tourettes regularly use marijuana and report that it calms them and eases their tics. And a few randomized clinical trials of delta 9-tetrahydrocannabinol, or THC, the active ingredient in marijuana, have been carried out. Some of the investigators are convinced that THC and related compounds in marijuana called cannabinoids are helpful; others are more equivocal.
The most comprehensive review to date of the efficacy of cannabinoids in Tourettes comes from a research group in Britain, the Cochrane Collaboration, that reviewed all the available data. They found that the improvements in tic frequency and severity were small and were only detected by some of the outcome measures. The group concluded that there is not enough evidence to support the use of cannabinoids in treating tics and obsessive-compulsive behavior in people with Tourettes syndrome.
More